Systemic thrombolysis therapy is associated with improved outcomes among patients with acute pulmonary embolism and respiratory failure
M Koslow, GE Shochet, F Fenadka, Y Neuman… - The American Journal of …, 2020 - Elsevier
Background Thrombolytic therapy is widely accepted for massive pulmonary embolism (PE)
due to the high mortality risk associated with standard anticoagulation alone. Its role in
submassive PE, however, has remained controversial. We aimed to evaluate whether the
selective use of systemic thrombolytic therapy with intravenous tissue plasminogen activator
(IV-tPA) improves the survival of patients with submassive PE at increased risk for clinical
deterioration. Methods A total of 184 consecutive patients diagnosed with acute PE by chest …
due to the high mortality risk associated with standard anticoagulation alone. Its role in
submassive PE, however, has remained controversial. We aimed to evaluate whether the
selective use of systemic thrombolytic therapy with intravenous tissue plasminogen activator
(IV-tPA) improves the survival of patients with submassive PE at increased risk for clinical
deterioration. Methods A total of 184 consecutive patients diagnosed with acute PE by chest …
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